Studies

Alzheimer’s Disease

SPONSOR: Alpha Cognition, Inc

STUDY NAME: A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE) (RESOLVE)

LINK: https://clinicaltrials.gov/study/NCT07633470

SPONSOR: Hoffmann-La Roche

STUDY NAME: A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease (PrevenTRON)

LINK: https://clinicaltrials.gov/study/NCT07717411

SPONSOR: Hoffmann-La Roche

STUDY NAME: A Study of Trontinemab in Participants with Early Symptomatic Alzheimer's Disease (TRONTIER 1)

LINK: https://www.clinicaltrials.gov/study/NCT07169578

SPONSOR: Hoffmann-La Roche

STUDY NAME: Screening Study to Determine Individuals with Potential Trial Eligibility for Alzheimer's Disease Studies (TRAVELLER)

LINK: https://clinicaltrials.gov/study/NCT07177352

SPONSOR: Lighthouse Pharmaceuticals, Inc.

STUDY NAME: Study of LHP588 in Subjects with P. Gingivalis-Positive Alzheimer's Disease

LINK: https://clinicaltrials.gov/study/NCT06847322

SPONSOR: NewAmsterdam Pharma

STUDY NAME: Randomized Study to Evaluate the Effect of Obicetrapib in Participants with Preclinical Alzheimer's Disease (SPINOZA)

LINK: https://clinicaltrials.gov/study/NCT07794670

Attention deficit/hyperactivity Disorder

SPONSOR: Alkermes, Inc.

STUDY NAME: A Study to Evaluate Safety and Efficacy of ALKS 7290 Compared with Placebo in Adult Participants With Attention Deficit Hyperactivity Disorder (ALKS 7290-201)

LINK: https://clinicaltrials.gov/study/NCT07755410

SPONSOR: Otsuka Pharmaceutical Development & Commercialization, Inc.

STUDY NAME: A Study to Test the Effects of Centanafadine in Adults with Attention-deficit/​Hyperactivity Disorder and Emotional Dysregulation

LINK: https://clinicaltrials.gov/study/NCT07759154

Bipolar Disorder

SPONSOR: Eli Lilly and Company

STUDY NAME: A Study of Brenipatide in Adult Participants with Bipolar Disorder (RENEW-Bipolar-1)

LINK: https://clinicaltrials.gov/study/NCT07286175

Borderline personality Disorder

SPONSOR: Boehringer Ingelheim

STUDY NAME: A Study to Test Different Doses of BI 1358894 and Find Out Whether They Reduce Symptoms in People with Borderline Personality Disorder

LINK: https://clinicaltrials.gov/study/NCT07717411

Generalized ANXIETY Disorder

SPONSOR: Otsuka Pharmaceutical Development & Commercialization, Inc.

STUDY NAME: A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults with Generalized Anxiety Disorder

LINK: https://clinicaltrials.gov/study/NCT07767903

Major Depressive Disorder

SPONSOR: atai Therapeutics, Inc.

STUDY NAME: A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

LINK: https://clinicaltrials.gov/study/NCT06524830

SPONSOR: Cybin IRL Limited

STUDY NAME: Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND) (EXTEND)

LINK: https://clinicaltrials.gov/study/NCT06605105

SPONSOR: Definium Therapeutics US, Inc.

STUDY NAME: A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

LINK: https://clinicaltrials.gov/study/NCT07592689

SPONSOR: Draig Therapeutics Ltd

STUDY NAME: A Study to Evaluate the Effectiveness of DT-101 in Patients with Depression (Tarian-1)

LINK: https://clinicaltrials.gov/study/NCT07300969

SPONSOR: Eli Lilly and Company

STUDY NAME: A Study to Investigate Adjunctive Treatment with Brenipatide Compared with Placebo in Delaying Time to Relapse in Adult Participants with Major Depressive Disorder (RENEWMDD-1)

LINK: Not Available

SPONSOR: Eli Lilly and Company

STUDY NAME: A Study of Brenipatide (LY3537031) in Adult Participants with Major Depressive Disorder (RENEW-MDD- 2)

LINK: https://clinicaltrials.gov/study/NCT07775300

SPONSOR: Janssen Research & Development, LLC

STUDY NAME: A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants with Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

LINK: https://clinicaltrials.gov/study/NCT03227224

SPONSOR: Janssen Research & Development, LLC

STUDY NAME: A Study to Evaluate Sleep Electroencephalogram (EEG) Features (Brain Activity While Sleeping) in Participants With Major Depressive Disorder (MDD)

LINK: https://clinicaltrials.gov/study/NCT07258485

SPONSOR: Janssen Research & Development, LLC

STUDY NAME: Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

LINK: https://clinicaltrials.gov/study/NCT06559306

SPONSOR: Xenon Pharmaceuticals Inc.

STUDY NAME: A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3) (X-NOVA3)

LINK: https://clinicaltrials.gov/study/NCT07076407

Opioid Use Disorder

SPONSOR: Eli Lilly and Company

STUDY NAME: A Study to Evaluate the Efficacy and Safety of Brenipatide as Adjunctive Treatment to Buprenorphine with or without Naloxone in Early Recovery of Participants with Opioid Use Disorder (RENEW-Op-1)

LINK: Not Available

Schizophrenia

SPONSOR: Eli Lilly and Company

STUDY NAME: A Study of Adjunctive Treatment with Brenipatide Compared to Placebo in Adult Participants with Schizophrenia (RENEW-Scz-1)

LINK: Not Available

SPONSOR: MapLight Therapeutics

STUDY NAME: A Long-Term Open-Label Study of ML-007C-MA in Adults with Schizophrenia

LINK: https://clinicaltrials.gov/study/NCT07459652

SPONSOR: Neurocrine Biosciences

STUDY NAME: NBI-1117568-SCZ3029: Evaluation of NBI-1117568 in Inpatient Adults with Schizophrenia

LINK: https://clinicaltrials.gov/study/NCT06963034

SPONSOR: Neurocrine Biosciences

STUDY NAME: NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults with Schizophrenia

LINK: https://clinicaltrials.gov/study/NCT07114874

Treatment Resistant Depression

SPONSOR: ACADIA Pharmaceuticals Inc.

STUDY NAME: ACP-211 Monotherapy for Major Depressive Disorder with Inadequate Antidepressant Response (NORLIGHT)

LINK: https://clinicaltrials.gov/study/NCT07284667

SPONSOR: atai Therapeutics, Inc.

STUDY NAME: A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)

LINK: https://clinicaltrials.gov/study/NCT06524830

SPONSOR: Janssen-Cilag International NV

STUDY NAME: A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/​Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder (ESCAPE-TRD)

LINK: https://clinicaltrials.gov/study/NCT04338321